Micro encapsulation of Naproxen By Complex Coacervation and Aqueous Colloid Dispersion Part ( 1 )

Micro encapsulation of Naproxen By Complex Coacervation and Aqueous Colloid Dispersion Part ( 1 )

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Naproxen is a non steroidal anti inflammatory and antipyretic drug which has local irritation effect on the stomach, and unpleasant taste, besides bad flowability and Basins - Emesis Basins light sensitivity.The drug was prepared as microcapsules by complex coacervation method using acacia-gelatin coating materials , and aqueous colloid polymer dispersion method ( ACPD ), using ethyl cellulose and sodium alginate coating materials.The results indicated that microcapsules prepared by 2:1 core:wall Ostomy Accessories ratio is the best for both methods, with an average encapsulation efficiency (75%) and avarege yield (90%).Moreover the drug release was affected mainly by core : ratio ,pH enviroment and method of microencapsulation.Key words: Naproxen,Microcapsule , Aqueaus colloid polymer dispersion.